Developing Agrochemical Formulations - New Challenges, Solutions and Trends

2019-03-07 admin click: 1727
Developing Agrochemical Formulations - New Challenges, Solutions and Trends
The number of pages:36 Release time:2019-03-07 Chart:6 Developing Agrochemical Formulations - New Challenges, Solutions and TrendsReport catalog Developing Agrochemical Formulations - New Challenges, Solutions and TrendsContent of the report Developing Agrochemical Formulations - New Challenges, Solutions and TrendsDownload the report
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Editor's Note: The formulation plays an essential role in achieving the successful delivery and biological activity of any plant protection product, while its development is facing a series of new challenges. Accordingly, AgroPages recently invited three key players: Syngenta, BASF Crop Protection and Arysta LifeScience to share their insights on the new challenges, key influencing factors and potential solutions of the agrochemical formulation development, as well as their innovation formulation technologies/products etc.

Developing Agrochemical Formulations - New Challenges, Solutions and Trends

Q1. What are the new challenges facing agrochemical formulation development, potential solutions and future trends?
Q2. What are the key factors in agrochemical formulation technology innovation? What initiatives did your company take to drive its innovation?
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Developing Agrochemical Formulations - New Challenges, Solutions and TrendsContent of the report

Q1. What are the new challenges facing agrochemical formulation development, potential solutions and future trends?

Syngenta: Resistance of pathogens or pests to chemical agents is not a new issue facing the agrochemical industry but it is one that remains a key challenge for agrochemical formulation development. With resistance comes the continued need for identification of new active ingredients and subsequently the need to formulate them into usable products. All the simple molecules have been discovered, so the pipeline of new compounds is trending to be increasingly complex — higher molecular weight, more diverse chemical functionality and multiple chiral centers are not uncommon. This subsequently imparts additional complexity on both manufacture of the active ingredient and in producing formulations that exhibit the desirable biology, application and shelf-life characteristics.

In my opinion, the fundamental solutions haven’t and won’t change. It’s about application of sound scientific know-how to work around the challenge. Through industry-leading formulation science, Syngenta is able to offer some of the best and yet most complex products in the marketplace. Formulations containing five, six and even seven active components in a single premix are common in Syngenta’s product portfolio. These products provide the convenience and dose accuracy of a single premix with multiple modes of action, providing broad-spectrum control of pests. The technical hurdles of physically and chemically compatibilized multiple active ingredients are done during formulation development, to mitigate these issues occurring in the mix tank at application.
 
The responsibility to produce new products that meet and exceed stewardship performance standards is an additional formulation challenge, whether it be reducing spray drift for aerial or ground spray application, dust reduction for seed treatments or improved operator safety. As formulation chemists, we’re looking to utilize innovative surfactant and coating technology to build in or tank mix additives that benefit or sustain biological activity, whilst addressing environmental challenges and the safe use of pesticides.

BASF Crop Protection: Challenges in formulation development should be discussed in the context of product development and how customers experience our products.

What makes a good product? From a famer's perspective, a product should be robust, flexible to use, efficient and performing, cost competitive, convenient, safe and without residue concerns. 

Developing robustness and flexibility in various weather conditions, such as rain, sun and wind, remain challenging for formulation development. To address these challenges, we focus on improvements in wash off, uptake, UV decomposition and off-target movements of active ingredients. Chemists develop polymeric stickers, surfactants, UV absorbers or drift reducing agents through proper formulation technology.

These improvements not only help a farmer run his operations profitably, but are also a crucial part of BASF’s sustainability strategy.

Other formulation trends are spurred by application constraints, such as low water volume or water quality, and from new application technologies, such as drones. Consequently, products must often be refined and adjusted so that in herent properties of the active ingredient, e.g. solubility and mixing compatibility, are managed effectively.

Arysta LifeScience: Modern agrochemical formulation development has faced significant challenges not only from a technical perspective, but also regulatory and market demands. The main challenges are:

The increasing demand for formulation quality, including the compatibility of multiple active ingredients in a single formulation and the controlled crystal growth of active ingredients.

The increasing regulatory pressures. Most regulatory authorities demand formulations that have minimal impact on the environment, which requires favorable ecotoxicity profiles with biodegradable additives, reduced use rate, and minimal pesticide residues on crops after spraying.  

The cost-effectiveness of new formulations.

While it is costly to develop new pesticides, formulation innovation has become a means to address the above challenges. For future trends, formulation innovation should not be separated from the improvement in application technologies. Instead, application technologies, such as precision agriculture, will also play a key role in reducing chemical drift and using pesticides effectively. 
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